Wine has been produced for thousands of years. The earliest evidence of wine is from ancient China (c. 7000 BC)​,​[1][2][3][4][5] Georgia (6000 BC)​,​[6][7] Persia (5000 BC)​,​ and Italy (4000 BC). New World wine has some connection to alcoholic beverages made by the indigenous peoples of the Americas​,​ but is mainly connected to later Spanish traditions in New Spain.[8] Later​,​ as Old World wine further developed viticulture techniques​,​ Europe would encompass three of the largest wine-producing regions. Today​,​ the five countries with the largest wine-producing regions are in Italy​,​ Spain​,​ France​,​ the United States​,​ and China.[9] Wine has long played an important role in religion. Red wine was associated with blood by the ancient Egyptians[10] and was used by both the Greek cult of Dionysus and the Romans in their Bacchanalia; Judaism also incorporates it in the Kiddush​,​ and Christianity in the Eucharist. Egyptian​,​ Greek​,​ Roman​,​ and Israeli wine cultures are still connected to these ancient